RCB Logo
RCB Logo




Building

हिन्दी / English

Details about RCB Patents

Patents Filed

Patent 1. Conjugated Anti-proliferative Drug Nano-particles and Process for Preparation thereof
Sreekanth Vedagopuram, Sandeep Kumar, Sagar Sengupta, and Avinash Bajaj Indian Patent Application No. 201611021486. 21 June, 2017.
This invention is related to development of nanomaterials for drug delivery based on modified steroidal lipids conjugated to drugs/diagnostic agents that can improve the bioavailability, solubility and therapeutic efficacy of existing chemotherapeutics. This invention includes methods of production of bile acid derivatives modified with suitable head groups (Phosphocholine, Polyethylene glycol/oligopeptides) based nanomicelles by nanoprecipitation/emulsion/solvent evaporation/dialysis etc consist of single/multiple therapeutics or imaging agents for treatment of cancer microbial infection, and inflammatory disease using parental routes (intravenous, subcutaneous).

Patent 2. Amphiphilic Cationic Polyelectrolytes and Nanoformulations Thereof
Prabhu S. Yavvari, Avinash Bajaj, and Aasheesh Srivastava
Indian Patent Application No. 201711023939. 09 July, 2018.
The present embodiment relates to polymeric nanogel formulations, and more particularly to nanogel formulations for delivery of therapeutic, diagnostic and theranostic cargos/loads such as siRNA, miRNA, plasmid DNA (pDNA), proteins, peptides, drugs and inorganic nanomaterials (Au, Ag, SiO2), or any combination/conjugates thereof.

Patent 3. Molecular Probes for detection of mycobacteria
Avinash Bajaj, Siddhi Gupta, Sandeep Kumar and Deep Kumar Mishra
Indian Patent Application No. 201811016154. 22 April, 2019.
The patent describes design and synthesis of a molecular probe that can be used to diagnose cases of extra pulmonary tuberculosis and differentiate them from non-tuberculosis infection cases affecting the same region. The simple chemical synthesis, easy derivatization and small size makes this probe novel as well as different. The uniqueness of this probe is its ability to selectively target mycobacteria even in a mixture of other bacterial species thus helping in the accurate diagnosis of extra pulmonary tuberculosis which is otherwise very challenging. We have shown the potential of this probe in detecting mycobacteria in clinical gastrointestinal tuberculosis samples and also in differentiating the cases of gastrointestinal tuberculosis with those of Crohn’s disease. The probe holds a strong potential to be used for clinical diagnosis owing to easy synthesis and maintenance, versatile ways of application, quick results as well as cost effectiveness.

Patent 4. m-Tor independent autophagy inducing small peptide and therapeutic uses thereof
Asthana S, Suri C, Kalia M, Awasthi A, Chande A, Rode A B, Prajapat S, Shadhu S, Bhardwaj V and Ojha D
Indian Patent Application No. 202011007117. February, 2020
The present invention is related to use of autophagy-inducing peptides. Autophagy is a cellular pathway that is upregulated during stress and disease conditions. Small peptides have been designed that upregulate autophagy. These peptides can have therapeutic implications in various disease states or conditions where autophagy upregulation is likely to be beneficial.

Patent 5. Water Soluble Fullerene C60 Adducts for Nano-Medicine & Materials Science
Prasenjit Guchhait and SV Eswaran
Indian Patent Application No. 202011007117. June 2018
This patent application proposes the use of Water Soluble Fullerene C60 adducts and metal complexes as anti-neoplastic or anti-cancer agents.



Patents Granted

Microorganisms for enhanced production of 2,3 butanediol and uses thereof
Nidhi Adlakha, Munjal N
Indian patent application number 337873. June 2020
The present innovation is related to modification of metabolic pathways for the fermentative production of 2, 3-butanediol, in order to enhance the yield and productivity. 2,3-Butanediol is a versatile bulk chemical with a huge market of ~320 billion USD, owing to its wide application in the manufacture of printing inks, perfumes, fumigants, moistening and softening agents, explosives, plasticizers, foods, pharmaceuticals, etc. Currently, it is derived from crude oil fractionation, but due to limited reserves and increasing prices of crude oil, the price hike for 2,3-butanediol (2,3-BDO) is indispensable. For this, we have engineered non-pathogenic Paenibacillus polymyxa using synthetic biology approach. Two enzymes butanediol dehydrogenase and acetolactate synthase were overexpressed whereas alcohol dehydrogenase was knocked out to achieve 60% increase in butanediol yield.

Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 3 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 3 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 3 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 3 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 3 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 3 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 3 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 5 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 3 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 3 Grouped Photo 5 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 3 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 2 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 2 Grouped Photo 2 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 2 Grouped Photo 3 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 3 Grouped Photo 4 Grouped Photo 5 Grouped Photo 2 Grouped Photo 2 Grouped Photo 3