Vancomycin-resistant Enterococci (VRE) have emerged as a significant public health issue due to their ability to cause various nosocomial infections, including catheter-associated urinary tract infections (CAUTIs). VRE employs endocarditis and biofilm-associated pili (Ebp) for adherence, which constitutes the initial step in biofilm formation.

The field of synthetic biology has fundamentally changed the development of microbial cell factories, enabling the efficient biomanufacturing of high-value chemicals and materials from sustainable feedstocks. The engineering of these bio-factories depends on the capacity to precisely govern the expression levels of numerous genes, which in turn facilitates the programming of cellular functions to achieve desired outcomes.

Botrytis cinerea, the gray mold fungus, is infamous for causing devastating losses in agriculture, yet its precise mode of infection remains incompletely understood. In a recent study led by Dr Nidhi Adlakha’s lab, a novel proteomics approach has shed light on the dynamic protein landscape of B. cinerea during host invasion.