inner-bg.png

2025

Unlocking the polysaccharide potential: A Novel Enzyme That Remodels Cell Walls to Boost Immunity

Polysaccharide acetylation plays a crucial role in plant development and is regulated by acetyltransferases and esterases located in the Golgi, plasma membrane, or cell wall. The role of acetylesterases in plant cell walls remains poorly understood. We investigated Arabidopsis GELP53, a member of the GDSL Esterase/Lipase Protein (GELP) family, which is localized in the plasma membrane. Our structural and biochemical analyses showed that GELP53 acts as a xyloglucan acetyl esterase, marking the first report of this enzyme in plants.