Research Highlights | Regional Centre for Biotechnology

Schematic illustration of pancreatic cancer showing a regulatory loop driven by epigenetics. Epigenetics-driven differential transcription upregulates NFAT2, leading to transcriptional upregulation of the calcium channel Orai3 at the plasma membrane, while March8 promotes lysosomal degradation.

One Factor, Two Fates: How NFATc1 Controls Orai3 in Pancreatic Cancer

Schematic illustration of a drug-loaded implant releasing a doxorubicin–STING agonist conjugate. The implant enables sustained delivery in mice—up to 4 months in the brain and 8 months via subcutaneous administration.

Long-lasting Hydrogel Mitigates Tumour Regression

Schematic diagram illustrating two pathways of Ataxin-3 aggregation as PolyQ length increases.

Decoding Ataxin-3 Phase Behavior in Spinocerebellar Ataxia Type 3

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