Disease Biology Laboratory

Major Focus:
Investigating Signaling Pathways of Thrombosis, Inflammation, and Innate and Adaptive Immune Responses in Human Health and Diseases, and Identifying Biomarkers and Molecular Targets to Develop Potential Therapeutics.

SARS-CoV-2 infection: ARDS and pulmonary fibrosis and host immune response

Dengue virus (DENV) and Japanese encephalitis virus (JEV) infection: pathogenesis and host immune response

DENV: heterotypic infection and host immune response

Viral infections in diabetes: severity and host immune response

Diabetes: pathogenesis of inflammation, thrombosis and pulmonary fibrosis

Genetic polymorphism and high altitude adaptation in Tibetan highlanders

Diabetes in highlander population

Hemolytic disorders: pathogenesis of inflammation and thrombosis

Autoimmune disorders: pathogenesis of inflammation and thrombophilia

• Sakshi Agarwal
  Senior Research Fellow
  sakshi.agarwal@rcb.res.in
• Anamika Singh
  Senior Research Fellow
  sakshi.agarwal@rcb.res.in
• Kishan K Gaur
  Junior Research Fellow
  kishan.gaur@rcb.res.in
• Garima Joshi
  Junior Research Fellow
  garima.joshi@rcb.res.in
• Garima Verma
  Junior Research Fellow
  garima.verma@rcb.res.in
• Tejeswara Rao Asuru
  Junior Research Fellow
  tejeswara.rao@rcb.res.in
• Shalu Singh
  Junior Research Fellow
  shalu.singh@rcb.res.in

Original Articles
1. Singh A, Ghosh R, Asuru TR, Prajapat S, Joshi G, Gaur KK, Shrimali NM, Ojha A, Vikram NK, Poncz M, Kalia M, Guchhait P* (2023) Inhibition of platelet factor 4:CXCR3 pathway prevents JEV and DENV infection. Journal of Thrombosis and Haemostasis, doi.org/10.1016/j.jtha.2023.11.015.
2. Agarwal S, Saha S, Ghosh R, Sarmadhikari S, Asthana S, Maiti TK, Khadgawat R, Guchhait P* (2023) Elevated glycosylation of CD36 in platelets is a risk factor for oxLDL mediated platelet activation in type 2 diabetes. FEBS Journal, https://doi.org/10.1111/febs.16976.
3. Singh A, Ghosh R, Guchhait P* (2023) CXCR3 antagonist rescues ER stress and reduces inflammation and JEV infection in mice brain. Cytokine, 7:172:156380. 10.1016/j.cyto.2023.156380.
4. Agarwal S, Ghosh R, Verma G, Khadgawat R, Guchhait P* (2023) Alpha-ketoglutarate supplementation reduces inflammation and thrombosis in type 2 diabetes by suppressing leukocytes and platelet activation. Clinical and Experimental Immunology, https://doi.org/10.1093/cei/uxad086.
5. Agarwal S, Kaur S, Asuru TR, Joshi G, Shrimali NM, Singh A, Singh ON, Srivastva P, Shrivastava T, Vrati S, Surjit M, Guchhait P* (2022) Dietary αKG inhibits SARS CoV-2 infection and rescues inflamed lungs to restore normal O2 saturation by inhibiting pAkt. Clinical and Translational Medicine e1041,12(9):1-6.
6. Shrimali NM, Agarwal S, Kaur S, Bhattacharya S, Bhattacharyya S, Prchal JT, Guchhait P* (2021) KG inhibits thrombosis and inflammation by prolyl hydroxylase-2 mediated inactivation of phospho-Akt. EBioMedicine 73:103672.
7. Bhattacharya S, Shrimali NM, Mohammad G, Koul PA, Prchal JT and Guchhait P*. (2021) Gain-of-function Tibetan PHD2D4E;C127S variant suppresses monocyte function: a lesson in inflammatory response to inspired hypoxia. EBioMedicine 68:103418.
8. Bhasym A, Annarapu GK, Saha S, Shrimali NM, Gupta S, Seth T, Guchhait P*. (2019) Neutrophils develop rapid proinflammatory response after engulfing Hb-activated platelets under intravascular hemolysis. Clinical and Experimental Immunology, doi: 10.1111/cei.13310.
9. Bhasym A, Gurjar BS, Sriharsha TM, Prabhu S, Puraswani M, Khandelwal P, Saini H, Saini S, Verma AK, Chatterjee P, Bal V, George A, Sharma A, Hari P, Sinha A, Bagga A, Rath S, Guchhait P*(2019) Altered Peripheral Blood Leucocyte Phenotype and Responses in Healthy Individuals with Homozygous Deletion of FHR1 and FHR3 Gene.Journal of Clinical Immunology, doi.org/10.1007/s10875-019-00619-2
10. R Singhal, DK Rathore, T Bhakuni, T Seth, P Guchhait* (2019) Absence of Non-classical Monocytes in Hemolytic Patients: Free Hb and NO-Mediated Mechanism. Journal of Immunology Research, doi.org/10.1155/2019/1409383
11. Ojha A, Bhasym A, Mukherjee S, Annarapu GK, Bhakuni T, Akbar I, Seth T, Vikram NK, Vrati S, Basu A, Bhattacharyya S, Guchhait P* (2019) Platelet factor 4 promotes rapid replication and propagation of Dengue and Japanese encephalitis viruses. EBioMedicine, 39: 332-347
12. Singhal R, Chawla S, Batra H, Gupta S, Ojha A, Rathore DK, Seth T and Guchhait P* (2018) Engulfment of Hb-activated platelets differentiates monocytes into pro-inflammatory macrophages in PNH patients. European Journal of Immunology. 48(8):1285-1294 doi: 10.1002/eji.201747449.
13. Singhal R, Chawla S, Rathore D, Bhasym A, Annarapu GK, Sharma V, Seth T, Guchhait P* (2016) Development of pro-inflammatory phenotype in monocytes after engulfing Hb-activated platelets in hemolytic disorders. Clinical Immunology, doi:10.1016/ j.clim.2016.12.007.
14. Singhal R, Annarapu GK, Pandey A, Chawla S, Ojha A, Gupta A, Cruz MA, Seth T, Guchhait P* (2015) Hemoglobin interaction with GP1b-alpha induces platelet activation and apoptosis: a novel mechanism associated with intravascular hemolysis. Haematologica 100(12): 1526-33.
15. Da Q, Teruya M, Guchhait P, Teruya J, Olson JS, Cruz MA*. (2015) Free hemoglobin increases von Willebrand factor-mediated platelet adhesion in vitro: implications on circulatory devices. Blood. 126(20):2338-41.
16. Lorenzo LR, Huff C, Myllymäki M, Olenchock B, Swierczek S, Tashi T, Gordeuk V, Wuran T, Li GR, McClain DL, Khan TM, Koul PA, Guchhait P, Salama ME, Xing J, Semenza GL, Liberzon E, Wilson A, Simonson TS, Jorde LB, Kaelin Jr WG, Koivunen P & Prchal JT* (2014) A genetic mechanism for Tibetan high-altitude adaptation. Nature Genetics, 46:951-956.
17. Zhou Z, Thiagarajan P, Udden MA, Lopez JA, Guchhait P* (2011) Membrane sulfatide plays a crucial role in the sickle erythrocytes adhesion to matrix and endothelial ligands. Thrombosis and Haemostasis. 105:1046-52.
18. Zhou Z, Han H, Cruz MA, Jose JA, Dong JF, Guchhait P* (2009) Hemoglobin blocks von Willebrand factor proteolysis by ADAMTS-13: a mechanism associated with sickle cell disease. Thrombosis and Haemostasis, 101 (6): 1070-77.
19. Guchhait P*, Shrimpton C, Honke K, Rumbaut R, Lopez JA, Thiagarajan P (2008) Effects of an anti-sulfatide single-chain antibody probe on platelet function. Thrombosis and Haemostasis, 99(3):552-57.

Original Articles
1. Singh A, Ghosh R, Asuru TR, Prajapat S, Joshi G, Gaur KK, Shrimali NM, Ojha A, Vikram NK, Poncz M, Kalia M, Guchhait P* (2023) Inhibition of platelet factor 4:CXCR3 pathway prevents JEV and DENV infection. Journal of Thrombosis and Haemostasis, doi.org/10.1016/j.jtha.2023.11.015
2. Agarwal S, Saha S, Ghosh R, Sarmadhikari S, Asthana S, Maiti TK, Khadgawat R, Guchhait P* (2023) Elevated glycosylation of CD36 in platelets is a risk factor for oxLDL mediated platelet activation in type 2 diabetes. FEBS Journal, https://doi.org/10.1111/febs.16976
3. Singh A, Ghosh R, Guchhait P* (2023) CXCR3 antagonist rescues ER stress and reduces inflammation and JEV infection in mice brain. Cytokine, 7:172:156380. 10.1016/j.cyto.2023.156380
4. Agarwal S, Ghosh R, Verma G, Khadgawat R, Guchhait P* (2023) Alpha-ketoglutarate supplementation reduces inflammation and thrombosis in type 2 diabetes by suppressing leukocytes and platelet activation. Clinical and Experimental Immunology, https://doi.org/10.1093/cei/uxad086
5. Kumari Sharda, Bandyopadhyay Bhaswati, Singh Anamika, Aggarwal Suruchi, Yadav Amit, Vikram Naval, Guchhait Prasenjit and Banerjee Arup (2023) Extracellular vesicles recovered from plasma of severe dengue patients induced CD4+T cell suppression through PD-L1/PD1 interaction. mBIO (accepted).
6. Gupta A, Sood A, Bhardwaj D, Shrimali N, Singhmar R, Chaturvedi S, Guchhait P, Agrawal G* (2023) Functionalized Chitosan Decorated Hafnium Oxide@Gold Core-Shell Nanoparticles for Multimodal Cancer Therapy. Advanced Therapeutics (accepted).
7. Agarwal S, Kaur S, Asuru TR, Joshi G, Shrimali NM, Singh A, Singh ON, Srivastva P, Shrivastava T, Vrati S, Surjit M, Guchhait P* (2022) Dietary αKG inhibits SARS CoV-2 infection and rescues inflamed lungs to restore normal O2 saturation by inhibiting pAkt. Clinical and Translational Medicine e1041,12(9):1-6.
8. Gupta A, Sood A, Dhiman A, Shrimali N, Singhmar R, Guchhait P, Agarwal G*. (2022) Redox Responsive Poly(allylamine)/Eudragit S-100 Nanoparticles for Dual Drug Delivery in Colorectal Cancer. Biomaterials Advances 143:e213184.  
9. Thakur SK, Ghosh R, Gaur KK, Guchhait P, Eswaran SV* (2022) Anti-cancer activity of water soluble reduced Graphene oxide-aryl arizidino manganese II complex. J Biomedical Nanotechnology 18:1-8.
10. Mohanbhai SJ, Sardoiwala MN, Gupta S, Shrimali NM, Roy Choudhury S, Sharma SS, Guchhait P, Karmakar S* (2022) Colon targeted chitosan-melatonin nanotherapy for preclinical inflammatory bowel disease. Biomaterials advances doi.org/10.1016/j.bioadv.2022.212796
11. Gautam D, Kailashiya J, Tiwari A, Chaurasia RN, Annarapu GK, Guchhait P, Dash D* (2022) Fibrinogen mitigates prion-mediated platelet activation and neuronal cell toxicity. Frontiers Cell and developmental Biology, doi: 10.3389/fcell.2022.834016
12. Kaur S, Singh A, Kaur J, Verma N, Pandey AK, Das S, Bhattacharyya S, Guchhait P* (2022) Upregulation of cytokine signaling in platelet increases risk of thrombophilia in severe COVID-19 patients. Blood Cells Molecules and Diseases, 94:102653
13. Chaudhury N, Srivastava S, Dave U, Ojha A, Guchhait P, Chandele A, Patel AK*. (2022). High-mobility group box 1 protein promotes dengue virus replication by interacting with untranslated regions of viral genome. Virus Research, 309:198668.
14. Shrimali NM, Agarwal S, Kaur S, Bhattacharya S, Bhattacharyya S, Prchal JT, Guchhait P* (2021) αKG inhibits thrombosis and inflammation by prolyl hydroxylase-2 mediated inactivation of phospho-Akt. EBioMedicine (In Press).
15. Bhattacharya S, Shrimali NM, Mohammad G, Koul PA, Prchal JT and Guchhait P*. (2021) Gain-of-function Tibetan PHD2D4E;C127S variant suppresses monocyte function: a lesson in inflammatory response to inspired hypoxia. EBioMedicine 68:103418.
16. Srivastava S, Chaudhary N, Ojha A, Guchhait P, Patel AK*. (2021) Signal transducer and activator of transcription 3 (STAT3) acts as a proviral factor for dengue virus propagation. Virus Research 300:198436.
17. Thakur S, Saha S, Guchhait P, Eswaran S*. (2020) Fullarazirman, nano water-soluble Fullerene C60-Mn (II) Triadduct complex with anti-cancer activity comparable to Doxorubicin. J Biomedical Nanotechnology. 16:481-491.
18. Thakur S, Goswami K, Rao P, Kaushik S, Singh B, Sharma PK, Asthana S, Bhattacharjee S, Guchhait P, Eswaran S*. (2020) A Fluoresceinated Aminohexanol Tethered Inositol Hexakisphosphate: Studies on Arabidopsis thaliana, Drosophila melanogaster and Docking with 2P1M Receptor. ACS Omega, 0c00961.
19. Sardoiwala N M, Kushwaha A, Dev A, Nishith S, Guchhait P, Karmakar S, Roy Choudhury S*. (2020) Hypericin loaded transferrin nanoparticles induce PP2A regulated BMI1 degradation in colorectal cancer specific chemo-Photodynamic Therapy. ACS Biomaterials Science & Engineering, 6,5, 3139-3153.
20. Sood A, Dev A, Mohanbhai SJ, Shrimali N, Kapasiya M, Kushwaha A, Choudhury SR, Guchhait P, Karmakar S* (2019) Development and targeting efficacy of disulfide bridged chitosan-Eudragit S-100 nanoparticles for colorectal cancer, ACS Applied Nano Materials. 2, 10: 6409-17.
21. Thakur S, Goswami K, Bhattacharjee S, Soni U, Guchhait P, Eswaran S*. (2019) A Water Soluble Single Walled Carbon Nanotube Aryl Aziridino Carboxylic Acid Decorated Mn (II) Complex Increased Root Growth in Arabidopsis thaliana. Chemistry Select. 201904205.
22. Bhasym A, Bhakuni T and Guchhait P* (2019) Elevated surface-bound complement factor-H alters the function of platelets and monocytes in FHR1/3-null healthy individuals. Blood Cells Molecules Diseases, 79:102349.
23. Bhasym A, Annarapu GK, Saha S, Shrimali NM, Gupta S, Seth T, Guchhait P*. (2019) Neutrophils develop rapid proinflammatory response after engulfing Hb-activated platelets under intravascular hemolysis. Clinical Experimental Immunology, doi: 10.1111/cei.13310
24. Bhakuni T, Singhal R, Aannarapu GK, Sharma A, Mahapatra M, Saxena R, Guchhait P* (2019) Unique case of autoantibody mediated inactivation of ADAMTS13 in an Indian TTP patient. Blood Cells Molecules Diseases, 77:29-33
25. Bhasym A, Gurjar BS, Sriharsha TM, Bhasym A, Prabhu S, Puraswani M, Khandelwal P, Saini H, Saini S, Verma AK, Chatterjee P, Bal V, George A, Sharma A, Hari P, Sinha A, Bagga A, Rath S*, Guchhait P* (2019) Altered Peripheral Blood Leucocyte Phenotype and Responses in Healthy Individuals with Homozygous Deletion of FHR1 and FHR3 Gene. J Clinical Immunology, doi.org/10.1007/s10875-019-00619-2
26. R Singhal, DK Rathore, T Bhakuni, T Seth, P Guchhait* (2019) Absence of Non-classical Monocytes in Hemolytic Patients: Free Hb and NO-Mediated Mechanism. Journal of Immunology Research, doi.org/10.1155/2019/1409383
27. Ojha A, Bhasym A, Mukherjee S, Annarapu GK, Bhakuni T, Akbar I, Seth T, Vikram NK, Vrati S, Basu A, Bhattacharyya S, Guchhait P* (2019) Platelet factor 4 promotes rapid replication and propagation of Dengue and Japanese encephalitis viruses. EBioMedicine, 39: 332-347
28. Singhal R, Chawla S, Batra H, Gupta S, Ojha A, Rathore DK, Seth T and Guchhait P*. (2018) Engulfment of Hb-activated platelets differentiates monocytes into pro-inflammatory macrophages in PNH patients. European J Immunology. 48(8):1285-1294 doi: 10.1002/eji.201747449.
29. Gurjar BS, Sriharsha TM, Bhasym A, Prabhu S, Puraswani M, Khandelwal P, Saini H, Saini S, Verma AK, Chatterjee P, Guchhait P, Bal V, George A, Rath S, Sahu A, Sharma A, Hari P, Sinha A, Bagga A. (2018) Characterization of genetic predisposition and autoantibody profile in atypical hemolytic uremic syndrome. Immunology. 154, 663-672. doi: 10.1111/imm.12916.
30. Ojha A, Nandi D, Batra H, Singhal R, Annarapu GK, Bhattacharyya S, Seth T, Dar L, Medigeshi GR, Vrati S, Vikram NK, Guchhait P*. (2017) Platelet activation determines the severity of thrombocytopenia in dengue infection. Scientific Reports, 7:41697.
31. Tashi T, Reading NS, Moore LG, Wuren T, Hu H, Teng F, Shestakova A, Lorenzo F, Burjanivova T, Koul P, Guchhait P, Wittwer C, Julian CG, Shah B, Huff CD, Ge R, Gordeuk VR, Prchal JT*. (2017) Gain-of-Function EGLN1 Prolyl Hydroxylase (PHD2 D4E:C127S) in Combination with EPAS1 (HIF2α) Polymorphism Lowers Hemoglobin Concentration in Tibetans. Journal of Molecular Medicine, p1-6.
32. Singhal R, Chawla S, Rathore D, Bhasym A, Annarapu GK, Sharma V, Seth T, Guchhait P*. (2016) Development of pro-inflammatory phenotype in monocytes after engulfing Hb-activated platelets in hemolytic disorders. Clinical Immunology, doi:10.1016/ j.clim.2016.12.007.
33. Annarapu GK, Singhal R, Gupta A, Chawla S, Batra H, Seth T, and Guchhait P*. (2016) HbS binding to GP1bα activates platelets in sickle cell disease. PLoS One, 11(12): e0167899. doi:10.1371/journal.
34. Annarapu GK, Singhal R, Peng Y, Guchhait P*. (2016) Inhibition of Hb binding to GP1bα abrogates Hb-mediated thrombus formation on immobilized VWF and collagen under physiological shear stress. PLoS One, 11(4):e0154276.
35. Singhal R, Annarapu GK, Pandey A, Chawla S, Ojha A, Gupta A, Cruz MA, Seth T, Guchhait P*. (2015) Hemoglobin interaction with GP1balpha induces platelet activation and apoptosis: a novel mechanism associated with intravascular hemolysis. Haematologica 100(12): 1526-33.
36. Da Q, Teruya M, Guchhait P, Teruya J, Olson JS, Cruz MA*. (2015) Free hemoglobin increases von Willebrand factor-mediated platelet adhesion in vitro: implications on circulatory devices. Blood. 126(20):2338-41.
37. Lorenzo LR, Huff C, Myllymäki M, Olenchock B, Swierczek S, Tashi T, Gordeuk V, Wuran T, Li GR, McClain DL, Khan TM, Koul PA, Guchhait P, Salama ME, Xing J, Semenza GL, Liberzon E, Wilson A, Simonson TS, Jorde LB, Kaelin Jr WG, Koivunen P & Prchal JT*. (2014) A genetic mechanism for Tibetan high-altitude adaptation. Nature Genetics, 46:951-956.
38. Zhou Z, Thiagarajan P, Udden MA, Lopez JA, Guchhait P*. (2011) Membrane sulfatide plays a crucial role in the sickle erythrocytes adhesion to matrix and endothelial ligands. Thrombosis Haemostasis. 105:1046-52.
39. Zhou Z, Han H, Cruz MA, Jose JA, Dong JF, Guchhait P*. (2009) Hemoglobin blocks von Willebrand factor proteolysis by ADAMTS-13: a mechanism associated with sickle cell disease. Thrombosis Haemostasis, 101 (6): 1070-77.
40. Guchhait P*, Shrimpton C, Honke K, Rumbaut R, Lopez JA, Thiagarajan P. (2008) Effects of an anti-sulfatide single-chain antibody probe on platelet function. Thrombosis Haemostasis, 99(3):552-57.
41. Dasgupta SK, Abdel-Monem H, Guchhait P, Nagata S, Thiagarajan P*. (2008) Role of lactadherin in the clearance of phosphatidylserine-expressing red blood cell in sickle cell disease. Transfusion, 48(11):2370-76.
42. Guchhait P, Dasgupta SK, Le A, Yellapragada S, Lopez JA, Thiagarajan P*. (2007) Lactadherin mediates sickle cell adhesion to the vascular endothelial cells in flowing blood. Hematologica, 92(9):1266-67.
43. Dasgupta SK, Guchhait P, Thiagarajan P*. (2006) Lactadherin binding and phosphatidylserine expression on cell surface-comparison with annexin A5. Translational Research, 148:19-25.
44. Lasser G, Guchhait P, Ellsworth J, Bishop P, Cruz MA, Lopez JA, Fruebis J*. (2006) C1q-TNF related protein-1 (CTRP-1), a vascular wall protein that inhibits collagen-induced platelet aggregation by blocking VWF binding to collagen. Blood, 107:423-430.
45. Guchhait P, Lopez JA, Thiagarajan P*. (2004) Characterization of autoantibodies against sulfatide from a V-gene phage-display library derived from patients with systemic lupus erythematosus. J. Immunol. Methods, 295: 129–137.
46. Bernardo A, Bergeron AL, Sun CW, Guchhait P, Cruz MA, Lopez JA, Dong JF*. (2004) Von Willebrand factor present in fibrillar collagen enhances platelet adhesion to collagen and collagen-induced platelet aggregation. J. Thromb. Haemost. 2(4): 660-9.
47. Guchhait P, Tosi MF, Smith CW, Chakraborty A*. (2003) The murine myeloid cell line 32Dcl3 as a model system for studying neutrophil functions. J. Immunol. Methods. 283(1-2): 195-204.

Review Articles

1. Joshi G, Dash A, Verma G, Guchhait P* (2023) Viral infection and host immune response in diabetes. IUBMB Life, (in press).
2. Shrimali MN, Agarwal S, Tiwari A, Guchhait P* (2022) Platelet-Neutrophil interactions and thrombo-inflammatory complications in type-2 diabetes mellitus. Current Physiology Reports, 10:1-10.
3. Bhattacharya S, Agarwal S, Shrimali SM and Guchhait P* (2021) Interplay between hypoxia and inflammation contributes to the progression and severity of respiratory viral diseases. Molecular Aspects of Medicine. 81:101000
4. Singh A, Bisht P, Bhattacharya S, Guchhait P*. (2020) Role of platelet cytokines in Dengue virus infection. Frontiers in Cellular and Infection Microbiology, 10:561366
5. Batra H, Chawla S, Singhal R, Annarapu GK, Guchhait P*. (2016) Cell free hemoglobin modulates phenotype and function of immune cells in hemolytic disorders. Austin Hematology, 1(1): 1007.
6. Bhattacharya S, Bhasym A, Guchhait P*. (2016) Insights into Cardiovascular Diseases: The Vicious Platelet-Immune System Loop. Cardiology: Open Access, 1(1):1-7.
7. Annarapu GK, Singhal R, Chawla S, Ojha A, Guchhait P*. (2016) Hemoglobin mediated regulation of platelet functions. Journal of Hematology and Transfusion, 4(3): 1052.
8. Pandey A, Chawla S, Guchhait P*. (2015) Type-2 diabetes: Current understanding and future perspectives. IUBMB Life. 67:506.
9. Chawla S., Singhal R., Guchhait P*. (2014) Hypertension in hypoxia. Hypertension Cardiol. 1 (3): 1-16.
10. Zhou Z, Yee D, Guchhait P*. (2012) Molecular link between intravascular hemolysis and vascular occlusion in sickle cell disease. Current Vascular Pharmacology. 10(6):756-61.
11. Zhou Z, Behymer M, Guchhait P*. (2011) Role of extracellular hemoglobin in thrombosis and vascular occlusion in patients with sickle cell anemia. Anemia. 10.1155/2011/918916.
12. Zhou Zhou, Prasenjit Guchhait*. (2010) Extracellular Hemoglobin regulation of von Willebrand factor activity. US Oncology & Hematology, 7(2):150–2.
13. Zhou Z*, Nguyen T, Guchhait P, Dong JF*. (2010) Von Willebrand factor, ADAMTS-13, and Thrombotic thronbocytopenic purpura. Seminar in Thrombosis Hemostasis, 36:71-81.

Book Chapter

1. Tiwari RL, Annarapu GK, Guchhait P*. (2013) Pathophysiological consequences of hemolysis in sickle cell disease in "Sickle Cell Disease" (Ed. D Acuna-Costroviejo and I Rusanova). Nova Science Publishers, Inc. ISBN: 978-1-62618-774-0.